Psychiatry 2005 – ISSN: 1550-5952 – Volume 02 – Issue 06 – June 2005
Feature Article:
Extended Release Drug Delivery Strategies in Psychiatry: Theory to Practice
Steven J. Siegel, MD, PhD

Acknowledgment: This work was supported by the Stanley Medical Research Institute. address for correspondence: Steven J. Siegel, MD, PhD, Stanley Center for Experimental Therapeutics in Psychiatry, Clinical Research Building, Rm. 145a, 415 Curie Boulevard Philadelphia, PA 19104; Phone: (215) 573-0278; Fax: (215) 662-7903 E-mail: siegels@mail.med.upenn.edu Abstract Objective: An overview of the emerging field of long-term delivery strategies for improved convenience and adherence with psychiatric medications is provided. This review is motivated by the hypothesis that adherence to treatment is an important determinant of clinical outcomes in a wide range of settings and is particularly important in psychiatry practice where patients require treatment for months or years and premature discontinuation can have serious consequences for patient health and quality of life.